AI Drug Discovery Company

Discovering First-in-Class Medicines. Computationally.

Insivio is an AI drug discovery company building a 7-program in-house pipeline across oncology and rare disease — every candidate computationally generated, IP-protected, and advancing toward pharma out-licensing.

7 programs · 2 modalities
Oncology + rare disease
Built for pharma out-licensing
PIPELINE 7 ACTIVE
STAGE PRE-CLINICAL
PLATFORM V4.2.1
Pipeline
7
Active in-house programs
Cost Advantage
~1,000×
vs. enterprise platforms
Focus
ONCO
+ Rare Disease
Stage
Pre-IND
In silico complete
External Validation & Strategic Partnerships
Pharma Out-Licensing Ready
FDA Orphan Drug Pathway
EMA COMP Designation
IND-Ready Pipeline

7 programs. Discovered in silico. Built for licensing.

Our agentic AI platform runs all programs through the same 5-stage discovery workflow — from target validation through patent filing — before any wet-lab spend.

insivio.engine  /  drug_discovery.pipeline

RUNNING · 00:00:00
01 · TARGET
Target ID & Validation
programs7 / 7
02 · SCREEN
Virtual Library Screening
ZINC22 + Enaminecomplete
03 · LEAD
Lead Gen & Docking
hitsV4 closed
04 · ADMET
Safety Profiling
leadsreview
05 · IP + IND
Patent & Regulatory
filingsin prog.
[PIPELINE] 7 active programs initialized · V4.2 platform active
[INSV-3001] dossier closed — 108/108 physics gate passed
[INSV-4601] dossier closed — 91.7% physics · clinical-anchor confirmed
[INSV-2001] ADMET flag review — pre-CRO confirm required
[INSV-5001] hERG dual-model disagree — patch-clamp mandatory
[RNAi-006-007] sequence locked · delivery spec confirmed
[IP] patent preparation in progress · wet-lab freeze: active
View Full Pipeline → Licensing Enquiries
OUR APPROACH

Two modalities. One scientific foundation.

We focus where unmet need is highest and computational design is most powerful.

⚭ SMALL MOLECULEmod_01.sm

Precision small molecules.

Structure-based drug design, molecular docking, and AI-guided optimization produce candidates with validated targets, favorable ADMET profiles, and defensible IP positions — in indications eligible for FDA & EMA Orphan Drug Designation.

5
programs
ADMET
profiled
ODD
pathway
⚭ RNAi · GENE SILENCINGmod_02.rnai

Targeting the undruggable.

RNA interference candidates addressing disease-relevant genes where no small molecule solution exists. Advanced SORT-LNP delivery platforms reach target tissues with precision, opening therapeutic territory conventional discovery cannot access.

2
programs
LNP
delivery
Orphan
eligible
OUR ADVANTAGE

Four capabilities we have built into every program.

/ 01

In-house pipeline, not a service.

We own our drug candidates. Every program is computationally generated, IP-protected, and developed internally. Revenue comes from milestone payments and pharma royalties — not consulting.

/ 02

AI-native, not AI-augmented.

Our discovery process was designed around agentic AI from day one — the platform is the R&D infrastructure, not a layer on top of an existing process.

/ 03

IP discipline.

Every program runs freedom-to-operate analysis before significant development investment. Patent strategy is concurrent with discovery — not downstream of it.

/ 04

Regulatory by design.

Orphan designation, IND strategy, and CMC readiness are considered at the program design stage — not at exit. Four of seven programs are FDA & EMA ODD-eligible.

300M+PEOPLE · 7,000 RARE DISEASES · <5% TREATED

Rare diseases are not small problems.

More than 300 million people worldwide live with a rare disease. Fewer than 5% have an approved treatment. The barrier is not scientific — it is economic. Until now, the cost and complexity of drug discovery made rare disease programs financially unviable for all but the largest pharmaceutical companies.

By dramatically reducing the cost of computational discovery, Insivio builds robust, IP-protected programs in indications previously out of reach — and advances them toward Orphan Drug Designation with the scientific rigor regulators expect.

◆ FDA Orphan Drug ◆ EMA COMP ◆ IND-Ready Pathway
COMMERCIAL PLATFORMS

Two platforms. Built on the same engine.

The same agentic AI infrastructure powering Insivio’s in-house pipeline is available to external researchers and health consumers.

💊 RESEARCH PLATFORMprod_01.dd

Drug Discovery Platform

End-to-end computational drug discovery for academic labs, rare disease foundations, and biotech teams. Small molecule and RNAi workflows, AI-orchestrated. Pharma-grade in silico pipelines at a fraction of enterprise cost.

Explore the platform →
⚡ CONSUMER HEALTHprod_02.lt

LongeviTwin

Privacy-first biological age and longevity optimization platform. On-device AI processes your biomarkers and health data locally — your data never leaves your device. Personalized healthspan insights without surveillance.

Explore LongeviTwin →

We are building programs. We are looking for partners.

Whether you are investing, licensing, or engaging in a regulatory capacity — we are open for conversation.

📈

Investors

Insivio combines the capital efficiency of a technology company with the asset value of a pharmaceutical pipeline. Our AI platform generates proprietary candidates; our in-house programs are IP-protected, modality-diversified, and advancing toward preclinical milestones.

Request investor materials →
🔬

Pharma & Biotech

Our pipeline of small molecule and RNAi candidates is developed with out-licensing and co-development in mind. Programs arrive at partnership discussions with ADMET profiles, IP filings, competitive landscape analysis, and a clear regulatory pathway.

Explore licensing →
🏛

Regulatory & Academic

We are committed to proactive, transparent engagement with the FDA and EMA. Programs targeting rare indications are being advanced with Orphan Drug Designation as a foundational strategic objective under both FDA and EMA COMP procedures.

Regulatory enquiries →

Ready to partner on AI-discovered medicines?

Whether you are an investor, pharma business development team, or regulatory professional — we are open for conversation.

Why partner with Insivio?

Our programs arrive at partnership discussions documentation-ready: ADMET dossiers, IP filings, competitive landscape, and a clear regulatory pathway — reducing diligence time and de-risking early partnership decisions.

5 small molecule + 2 RNAi programs
Oncology · Hypertension · Urology
🏛
5 programs with FDA & EMA ODD eligibility
7-year US · 10-year EU market exclusivity
🔒
IP-first development
FTO cleared before every program advance

Express Interest

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